Systems biology with a view
نویسندگان
چکیده
منابع مشابه
A systems view of mRNP biology.
Gene expression occurs through a complex mRNA-protein (mRNP) system that stretches from transcription to translation. Gene expression processes are increasingly studied from global perspectives in order to understand their pathways, properties, and behaviors as a system. Here we review these beginnings of mRNP systems biology, as they have emerged from recent large-scale investigation of mRNP c...
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The genetic code has evolved from its initial non-degenerate wobble version until reaching its present state of degeneracy. By using the stereochemical hypothesis, we revisit the problem of codon assignations to the synonymy classes of amino-acids. We obtain these classes with a simple classifier based on physico-chemical properties of nucleic bases, like hydrophobicity and molecular weight. Th...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2006
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm2051